Amitraz
نویسندگان
چکیده
In the asymmetric unit of the title compound {systematic name: N'-(2,4-di-methyl-phen-yl)-N-[N-(2,4-di-methyl-phen-yl)carbox-imido-yl]-N-methyl-methanimidamide}, C19H23N3, which is a formamidine pesticide, there are two independent and conformationally similar mol-ecules, with the dihedral angle between the mean planes of the 2,4-di-methylbenzene rings in each mol-ecule being 41.63 (6) and 42.09 (5)°. The crystal structure is stabilized by a C-H⋯N hydrogen bond, as well as weak inter-molecular C-H⋯π and π-π inter-actions [ring centroid separation = 3.7409 (15) Å], giving one-dimensional chains extending down the b direction.
منابع مشابه
Effects of the insecticide amitraz, an alpha2-adrenergic receptor agonist, on human luteinized granulosa cells.
BACKGROUND Amitraz, an insecticide used to prevent tick and mite infestation of cattle, crops and dogs, is an alpha2-adrenergic receptor agonist that inhibits GnRH release and the ovulatory LH surge in rats. Noradrenalin, the physiological ligand for adrenergic receptors, inhibits progesterone production by IVF-derived granulosa cells, but the effects of amitraz are unknown. METHODS Luteinize...
متن کاملYohimbine and Atipamezole on the Treatment of Experimentally Induced Amitraz Intoxication in Cats
Experimental amitraz intoxication and its reversal by atipamezole and yohimbine were studied in cats. Twenty four cats were randomly divided equally into 3 groups: Group A (amitraz); Group AY (amitraz/yohimbine) and Group AA (amitraz/atipamezole). Sedation, loss of reflexes, hypothermia, bradycardia, bradyarrhythmia, hypotension, bradypnea, mydriasis, and initial transitory hyperglycemia occurr...
متن کاملProtective Effects of Propolis Against the Amitraz Hepatotoxicity in Mice
The present study aimed to study the protective effects of honeybee propolis against the amitraz hepatotoxicity in mice. Forty-eight Swiss albino male mice of 8 weeks of age, 22 to 25 g body weight were divided into four groups. The 1 was control, the 2 was treated orally with 150 mg kg propolis extract, the 3 was treated with 160 mg kg amitraz and the 4 one had 160 mg kg amitraz + 150 mg kg pr...
متن کاملAmitraz poisoning--an unusual pesticide poisoning.
AIMS OF THE STUDY To report the clinical features, laboratory findings and the management instituted for the patients with acute Amitraz Poisoning. METHODS AND MATERIAL Three cases of acute Amitraz Intoxication were studied and compared with previous reports from the literature. RESULTS All the three female cases were brought to our hospital with age ranging from 2 years to 40 years, consum...
متن کاملNear-fatal amitraz intoxication: the overlooked pesticide.
Amitraz is commonly used in agricultural industries throughout the world as a farm-animal insecticide. Despite its widespread use, amitraz intoxication is extremely rare and mainly occurs through accidental ingestion by young children. Severe, life-threatening amitraz intoxication in adults is very rarely recognized and reported. Described herein is a previously healthy 54-year-old patient who ...
متن کاملThe Development and Validation of an Analytical Method for Simultaneous Determination of Amitraz and Its Metabolite in Air Samples
Background: To determine the atmospheric contamination by pesticides, conducting laboratory studies is necessary before operating field studies. The aim of this research study was to develop an analytical method to sample and simultaneously determine airborne amitraz and its metabolite. Methods: A modified fritted impinger with acetonitrile as the liquid sorbent was used in order to study the a...
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